This discussion may contain spoilers!
For example, Toad would have given you some vital piece of info in the next episode, but doesn't because he doesn't trust you anymore for taking your sweet time to come help him.
As it stands, it seems like there is an objectively right decision in Episode 1: go to Lawrence's house first and you can save him. Don't go and he dies and not much changes with Toad except being scolded. In subsequent replays, therefore, everyone will know which one to pick.