I was just playing through some more Walking Dead Season 1 after your advice fixed my previous issue Episode 2 Black Screen and I pretty much encountered the same problems as GotRedOnYou in this post.
Only thing I can add was that the game had crashed prior to this issue, and after rebooting Steam on my Mac and relaunching the game, it opened in non-fullscreen, with a different resolution, and with no saves listed.
I was all but done Episode 4 (about to start the last chapter), I hope you can help me as well so I don't need to restart this game again. Although, I must say I am a bit worried, as I don't seem to have a large prefs.prof file in the typical places...
Thanks, and hoping for the best.